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Maryland State Police troopers are investigating a Monday afternoon accident in Prince Frederick that sent three people to the hospital.

At 2:02 p.m. Sept. 9, troopers from the MSP Prince Frederick barrack responded to a report of a serious car accident on Route 4 south of Westlake Boulevard, according to a press release.

Police determined a 2000 Ford F-150 truck, driven by 27-year-old Rebecca Murphy of Lusby, was heading south on Route 4 when it swerved from the left lane to the right lane, then back to the left lane. Police said Murphy lost control of the truck and crossed the center median into oncoming traffic heading north on Route 4, the release states.

A 2000 Jeep Cherokee, driven by Casey Jones, 22, of Waldorf was heading north in the left lane on Route 4 and was hit head-on by the Ford, police said. The Jeep then crossed the center median and hit a traffic sign, which “went airborne” and hit a 2009 BMW, driven by Stephanie Wright, 56, of Lusby, police said.

Jones, Murphy and a passenger in Murphy’s vehicle, 34-year-old Roger Murphy of Lusby, were all flown to Prince George’s Hospital Center and are currently listed in serious condition, the press release states.

The Calvert County Sheriff’s Office, Prince Frederick Volunteer Rescue Squad and Volunteer Fire Department, Calvert Advanced Life Support, State Highway Administration and St. Leonard and Huntingtown volunteer fire departments assisted with the incident, troopers said.

The investigation into the collision is ongoing and is being conducted by Tfc. S. Lewis of the Prince Frederick barrack.